Yildirim Cinar, An excellent. Mete Senyol, Kamber Duman, Blood viscosity and you will hypertension: part regarding temperatures and you can hyperglycemia, American Journal regarding Blood pressure level, Volume fourteen, Issue 5, , Users best gay hookup apps 2021 433–438,
Abstract
We planned a study to research the relations among blood pressure (BP), viscosity, and temperature in healthy subjects and among BP, viscosity, and glucose in diabetics. With simple random sampling method, 53 healthy and 29 diabetes mellitus (DM) type II subjects were selected. Parameters were determined with capillary viscometer and glucometer at 22°C, 36.5°C, and 39.5°C in healthy subjects, and at 22°C on diabetic patients during OGTT with 75 g of glucose. Statistical evaluations of the data were made with regression analysis, Student t test, Spearman’s correlation, and analysis of variance. When temperature decreased from 36.5°C to 22°C, blood viscosity increased %. This increase resulted in a % decrease in blood flow rate. According to the Hagen-Poiseuille equation, the required BP increase for compensation of the resulting tissue ischemia was %. Also, a % decrease in erythrocyte deformability and % increase in plasma viscosity were seen. When temperature increased from 36.5° to 39.5°C, blood viscosity decreased %. This caused % decrease in blood flow rate, and % decrease in BP, according to the equation. Erythrocyte deformability increase of 9.92% and plasma viscosity decrease of 4.99% arose from the temperature rise. There is a correlation between total data for temperatures and viscosities (r = ?0.84, P < .001). When the mean value of blood glucose increased from 100 to 400 mg/dL, viscosity increased 25% (r = 0.59, P = .002). In this state, blood flow rate decrease was 20% and BP increase for physiological compensation was 25%. Consequently, temperature, glucose and viscosity levels of blood are important factors for BP. Am J Hypertens 2001;–438 © 2001 American Journal of Hypertension, Ltd.
The aim of all of our study would be to look into the matchmaking certainly temperature, sugar focus, and you can viscosity of bloodstream and you will plasma, and estimate its consequences on the blood circulation pressure (BP) predicated on Hagen-Poiseuille’s hydrodynamics formula.
If the human circulatory system is considered as a closed system, hemodynamic equilibrium can be determined according to Poiseuille’s equation through the pressure, viscosity, flow rate, velocity of blood, and vessel diameter. Viscosity can be defined as the resistance of fluids against flow. The resistance for blood circulation includes friction between the blood elements and between the vessel lumen and blood. To make a fluid flow, the application of energy is required. Therefore, the energy of the circulatory system is spent in correlation with the viscosity level of blood. Energy forms of the circulatory system are BP and blood flow velocity. The velocity (v) and pressure of blood flow can be determined with Poiseuille’s equation as v = 1/4?L (F1 ? F2) (a 2 ? r 2 ), and also BP rate (Q) can be expressed from the above equation as Q = ?a 4 /8 ?L (F1 ? F2), where ? is the viscosity of the fluid, F1 and F2 are the initial and the final cross sectional pressures of blood, L is the length, a is the radius of vessel, and r is the distance from the center of the vessel for a flowing particle. 1, 2 Thus, to keep the equilibrium of the equation constant in the circulatory system, BP will increase when viscosity increases.
Blood viscosity and you will blood pressure: role regarding temperature and you will hyperglycemia
It has been found one between % and you can % values from hematocrit, all the eleven% rise in hematocrit increases blood viscosity of the 20%. Inside condition, based on Poiseuille’s equation, blood circulation rates decrease from the %, that could lead to cells ischemia. To save the brand new circulatory system inside the balance (that’s, staying the brand new flow price sufficient and you will preventing tissue ischemia), a 20% increase in BP or cuatro.66% vasodilation will become necessary. 3 However, the human being circulatory system is maybe not an accurate closed system, because blood viscosity will be altered to the intake away from dinner otherwise drugs. 4–8 At the same time, the effects from dietary fat and of particular drugs on bloodstream viscosity and you may hemodynamics eg BP had been said. Since atherosclerotic ships usually do not dilate good enough due to the fact a reaction to vasodilator drugs, it’s been suggested one improved bloodstream viscosity can only just feel settled having good BP increase in particularly products. 9–a dozen In addition to, the fresh matchmaking among BP, nightmare, coagulation, blood flow velocity, and bloodstream viscosity was in fact explained via the values of hemodynamics. thirteen, fourteen